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Chapter 15: Advances in Molecular Genetics

Practice Test
      
  1.What is a short piece of synthetic DNA that is added to DNA after electrophoresis?  
  a.   probe  
  b.   germ-line  
  c.   point mutation  
  d.   nonsense mutation  
  Hint    
      
  2.What is the study of DNA sequence information to help explain cell functions?  
  a.   polymerase chain reaction  
  b.   functional genomics  
  c.   restriction enzymes  
  d.   gel electrophoresis  
  Hint    
      
  3.What is a type of mutation in which one base pair changes into a different one?  
  a.   frameshift mutation  
  b.   point mutation  
  c.   gene amplification  
  d.   translocation  
  Hint    
      
  4.What is an international project that studies the genomes of humans and other organisms?  
  a.   Human Genome Project  
  b.   International Genome Project  
  c.   International Energy Project  
  d.   National Health Initiative  
  Hint    
      
  5.What were the first genomes to be sequenced by scientists?  
  a.   those of house cats  
  b.   those of viruses  
  c.   those of fruit flies  
  d.   those of bacteria  
  Hint    
      
  6.What is a type of mutation in which one or two base pairs are inserted or deleted from the DNA?  
  a.   translocation  
  b.   frameshift mutation  
  c.   nonsense mutation  
  d.   point mutation  
  Hint    
      
  7.What was the first eukaryotic organism to have its genome sequenced?  
  a.   Streptococci  
  b.   Escherichia coli  
  c.   Saccharomyces cerevisiae  
  d.   Caenorhabditis elegans  
  Hint    
      
  8.What are the most commonly used vectors in genetic engineering?  
  a.   plastids  
  b.   mitochondria  
  c.   ribosomes  
  d.   plasmids  
  Hint    
      
  9.What are genetic variations in which alleles differ by only one or a few scattered nucleotides?  
  a.   single nucleotide polymorphism  
  b.   RFLP analysis  
  c.   translocations  
  d.   polymerase chain reaction  
  Hint    
      
  10.What is the cause of muscular dystrophy?  
  a.   mutations in genes that encode muscle proteins  
  b.   translocation of chromosomes 9 and 22  
  c.   mutations in genes that encode cytochrome P450  
  d.   gene amplification of pancreas cells that produce insulin  
  Hint    

 
   
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